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Urinary Phthalate Metabolites Are Associated With Decreased Testosterone in Men, Women, and Children

John D. Meeker and Kelly Ferguson conducted a study to determine if urinary concentrations of 13 Phthalate metabolites correlated with low testosterone levels in men, women, and children. The reason for the study is evidence of declining testosterone levels among men in recent decades and in related conditions at multiple life stages and in both sexes. There is also animal and limited human evidence that exposure to phthalates, chemicals found in plastics and personal care products, is associated with reduced androgen levels and associated disorders.

The study found the presence of Phthalate metabolites in the urine correlated with a significant reduction in testosterone in men, women and 6-12 year old boys. In some cases the reduction in testosterone was as much as 29%.

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