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    Methylsulfonylmethane (MSM)


    Methylsulfonylmethane (MSM)

    What is it?

    Methylsulfonylmethane (MSM) is an organosulfur compound with the formula (CH3)2SO2. It is also known by several other names includingDMSO2, methyl sulfone, and dimethyl sulfone. This colorless solid features the sulfonyl functional group and is considered relatively inert chemically. It occurs naturally in some primitive plants, is present in small amounts in many foods and beverages, and is marketed as adietary supplement. It is also commonly found in the atmosphere above marine areas, where it is used as a carbon source by the airborne bacteria Afipia, and is found distinctively in human melanoma cells.

    Key Information

    • Hemorrhoids: Applying a gel containing MSM, hyaluronic acid, and tea tree oil seems to improve symptoms of hemorrhoids.
    • Osteoarthritis: Taking MSM by mouth seems to slightly reduce some symptoms of arthritis of the knee, such as pain and joint movement.

    More Information

    Other uses of MSM include eye inflammation, mucous membrane inflammation, temporomandibular joint (TMJ) problems, leg cramps, migraine, headaches,hangover, parasitic infections of the intestinal and urogenital tracts includingTrichomonas vaginalis and Giardia, yeast infections, insect bites, radiation poisoning, and to boost the immune system.


    This ingredient is commonly used in: