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    Glucosamine HCL


    Glucosamine HCL

    What is it?

    Glucosamine is usually made from seashells, or it can be made in the laboratory. Glucosamine hydrochloride is one of several forms of glucosamine.

    Key Information

    • High cholesterol: Early research suggests that glucosamine hydrochloride does not affect cholesterol or triglyceride levels in people with high cholesterol.
    • Knee pain: There is some early evidence that glucosamine hydrochloride might provide some pain relief for people who have regularly occurring knee pain as a result of joint injury.

    More Information

    Glucosamine in the body is used to make a “cushion” that surrounds the joints. In osteoarthritis, this cushion becomes thinner and stiff. Taking glucosamine hydrochloride as a supplement might help to supply the materials needed to rebuild the cushion.

    Early evidence shows that taking glucosamine hydrochloride, alone or with chondroitin sulfate, reduces pain and improves physical function in adults with a bone and joint disorder called Kashin-Beck disease. There is conflicting evidence about the effectiveness of glucosamine hydrochloride for osteoarthritis. Most of the evidence supporting the use of glucosamine hydrochloride comes from studies of a particular product (CosaminDS, Nutramax Laboratories) that contains a combination of glucosamine hydrochloride, chondroitin sulfate, and manganese ascorbate. Some evidence suggests that this combination can improve pain in people withknee osteoarthritis. This combination might work better in people with mild-to-moderate osteoarthritis than in people with severe osteoarthritis.


    This ingredient is commonly used in: