What is it?
An extract of the aerial parts of Chrysanthellum indicum, a flowering herb in the daisy family (Asteraceae). Researchers describe the extract as containing a combination of phenylpropenoic acids, flavonoids and saponins. In cosmetics it is used as a skin-conditioning ingredient, and it has been tested in a face cream for people with the redness of rosacea.
Key information
- In a 12-week placebo-controlled trial, 246 adults with moderate rosacea applied a cream with 1 percent Chrysanthellum indicum extract or a placebo cream twice a day.
- Adverse reactions in that trial were mild and did not differ between the extract and placebo groups.
- We found no safety assessment of the extract by the Cosmetic Ingredient Review or the EU's Scientific Committee on Consumer Safety.
More information
Chrysanthellum indicum is a flowering herb of the daisy family, and the cosmetic ingredient is made from the parts that grow above ground. According to the researchers who studied it, the extract contains phenylpropenoic acids, flavonoids and saponins and affects the permeability of small blood vessel walls, which is why it has been tested for facial redness.
The most useful safety information comes from a multicenter, randomized, double-blind trial published in 2005. It included 246 people aged 18 to 80 with moderate rosacea, who applied either a cream containing 1 percent Chrysanthellum indicum extract or a placebo cream to the face twice a day for 12 weeks. Adverse reactions were mild and did not differ between the two groups, and the researchers described the extract cream as well tolerated. Redness scores fell by 41.3 percent with the extract cream and 32.5 percent with the placebo cream.
Beyond that trial, published safety data are sparse. We found no safety assessment of the extract by the Cosmetic Ingredient Review (CIR) or the EU’s Scientific Committee on Consumer Safety, and no published case reports of allergic reactions to it. On labels it appears as Chrysanthellum Indicum Extract.
Sources: Journal of the European Academy of Dermatology and Venereology (2005): Randomized placebo-controlled trial of a flavonoid-rich plant extract-based cream in the treatment of rosacea; Molecules (2025): The use of plants that seal blood vessels in preparations applied topically to the skin: a review
